Research
Epitranscriptomics & Cancer Adaptation : A.David

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Our research work focuses on the contribution of post-transcriptional mechanisms on cancer cell adaptation, in particular RNA epigenetic & translational control.

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25 Items
Title  Creator  Group name  Publishing year 
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions Martins et al. EquipeJC Dec 2016
Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions Silva et al. EquipeJC Oct 18 2016
A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN Mazouzi et al. EquipeJC Apr 14 2016
[Radiomics: Definition and clinical development] Bourgier et al. EquipeJC Oct 2015
The RNA-binding protein HuR/ELAVL1 regulates IFN-beta mRNA abundance and the type I IFN response Herdy et al. EquipeJC May 2015
The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity Heinz et al. EquipeJC Jun 30 2015
Targeting a cell state common to triple-negative breast cancers Muellner et al. EquipeJC Jan 2015
Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage Bhattacharya et al. EquipeJC Nov 17 2015
Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling Huber et al. EquipeJC Nov 2015
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation Licciardello et al. EquipeJC Jul 2015
Germline RBBP6 mutations in familial myeloproliferative neoplasms Harutyunyan et al. EquipeJC Nov 16 2015
Gene essentiality and synthetic lethality in haploid human cells Blomen et al. EquipeJC Oct 15 2015
A surface biotinylation strategy for reproducible plasma membrane protein purification and tracking of genetic and drug-induced alterations Hormann et al. EquipeJC Dec 24 2015
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis Fauster et al. EquipeJC 2015
Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH Kainulainen et al. EquipeJC Mar 2014
TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens Muellner et al. EquipeJC 2014
The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia Sharif et al. EquipeJC Jun 2014
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy Huber et al. EquipeJC Apr 10 2014
Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics Gridling et al. EquipeJC Nov 2014
Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency Salzer et al. EquipeJC Jun 2014
Comprehensive comparative and semiquantitative proteome of a very low number of native and matched epstein-barr-virus-transformed B lymphocytes infiltrating human melanoma Maurer et al. EquipeJC Jun 6 2014
CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2 Boucheron et al. EquipeJC May 2014
Building and exploring an integrated human kinase network: global organization and medical entry points Colinge et al. EquipeJC Jul 31 2014
Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity Willmann et al. EquipeJC 2014
A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF Borgdorff et al. EquipeJC May 8 2014
25 Items


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Located in the Parc Euromédecine, the Institut de Recherche en Cancérologie de Montpellier (U1194) is located on the Val d'Aurelle Campus (ICM, Institut régional du Cancer Montpellier/ Val d'Aurelle).

U1194 Research Centre supported by Inserm, the University of Montpellier and the Institut du Cancer de Montpellier (ICM)

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Institut de Recherche en Cancérologie de
Montpellier (U1194) - Campus Val d'Aurelle

208 avenue des Apothicaires
34298 Montpellier cedex 5 FRANCE

 

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© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés